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TINSAL-T2D


Doris' Blog
By: dorisjdickson


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Islet Cells Generation - Cure? I Think Not! - Oct 01
This article in Diabetes Health discusses yet another new potential "cure."  However, yet again, it requires immunosuppressants which are not an option to me.  ...
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Cholesterol Conundrum - Sep 21
I recently wrote about Red Yeast Rice as an alternative to statins and the fact that it actually IS a statin since they contain the same active ingredients.  You just ...
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Red Yeast Rice - It is a Statin - Do I Take It? - Sep 10
I receive Dr. Mercola's newsletter regularly.  I don't, however, regularly read it.  My concern is the amount of "stuff" sold on the website.  However, this ...
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Diabetic ketoacidosis at onset of type 1 diabetes remains frequent in children - Sep 08
This article in yesterday's edition of Endocrine Today makes me scratch my head.  First and foremost, had this study been conducted in 1976 in the US and not in Germany, ...
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Inaccurate Monitors and Strips - Sep 02
Some of you may have read about the FDA's recent warning about the inaccuracy of certain test strips while taking certain medications.  Honestly, I didn't pay much attention ...
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Posted: Feb 3, 2009 19:10
  • 1 Comment.
  • TINSAL-T2D

    “TINSAL-T2D” is also known as Targeting Inflammation with Salsalate in Type 2 Diabetes.  The study of the goal is to further research the medication salsalate, discussed in the October 2008 edition of  Diabetes Health.  The initial study at the Joslin Diabetes Center in Boston showed the inexpensive aspirin-like drug used to treat arthritis showed a significant reduction in blood glucose levels as well as C-reactive protein, a marker for inflammation.

     

    The “TINSAL-T2D” study, funded by the National Institute of Diabetes and Digestive and Kidney Diseases, is using salsalate to target inflammation.  A second study, “TINSAL-IGT,” being performed at the Carl T. Hayden VA Medical Center in Phoenix, is aimed at helping patients with impaired glucose tolerance improve their sensitivity to insulin.

     

    For patients or family members who would like to participate, the one-year study requires the participation of 560 adults from age 18 to 75.  Participants must not be using insulin (although one or two oral medications are permissible) and must have poor blood sugar control. 

    If the medication continues to prove effective against high blood sugar and inflammation, the hope is to add salsalate to the arsenal of diabetes medications.  Since physicians have years of experience prescribing the medication for arthritis, it is already known to be inexpensive and safe – something not always the case with newer diabetes medications.  In addition, because of the relationship with inflammation, Joslin researchers are also hoping salsalate reduces the occurrence of coronary artery disease among type 2 diabetics. 

    More study information can be found at www.tinsalt2d.org.  The study leader is Allison B. Goldfine, MD and may be reached via e-mail at [email protected].

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  • By: FatCatAnna:

    Just wondering Doris - if this is sort of similar to my taking low dose aspirin but different effect? Something my endo has me taking - to help the blood flow better thru' my aging diabetic viens?  I have Type 2 friends that take low dose as well - as well as regular folks.

    I know a few of my diabetic friends have attempted to get into some of Allison Goldfines other diabetic studies.  She does some interesting work.



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