According to this article in today's online version of the Endocrine Today it is no more effective to attempt to screen type 2 patients looking for gene markers than it is to use the traditional risk factors (weight, blood pressure and actual glucose levels).
Not being one of those who believes that type 2 is "predominately" genetic, I can not say I am surprised. I am one of those who believes that there may be "some" genetics behind the scenes but that "nurture" has more to play in the onset of this versions of diabetes.
I believe that human bodies were not made for the eating and activity levels of today's man. We were men created to be active, survivalists who ate from the land. That means meat and fish and greens, etc. that were put here when we were.
Many indications are given that the "grain" evolution was the start of the our bodies trying but being unable to adapt. After all, as much as we love them, how long has it actually been since we could turn a healthy blueberry into a tasty but very unhealthy blueberry muffin?
I am also a firm believer that we do much of the damage to ourselves. Our bodies are just not intended to handle the volume of insulin we force them too. Even I, as a thin, insulin sensitive person can push my body to wear it doesn't want to be. On the days following "cheat" events I can see where glucose is just handled entirely different by my injections of insulin. I am much less sensitive after a Thanksgiving Day or other holiday event filled with more than my normal lower carb standard day. It just doesn't work.
Now, were I not be entirely insulin-dependent and testing my blood sugar repeatedly throughout the day, as well as keeping a log and analyzing my body's behavior, I would have no clue I too can create insulin resistance - by eating higher carb and thus requiring substantially more than normal insulin.
My point ... those who do not take insulin or have a meter and eat high carb day in and day out have no idea until they've done the damage that they are doing damage.
So ... therefore, I understand the results of this study (albeit there should be further studies/follow-up). I believe that you if you look at someone's day in and day out food/activity etc. diary, you are much more likely to predict the onset of type 2 diabetes than with any genetic testing.
But that's just one person's opinion ...
Doris J. Dickson